KCOTs are seen in about 75% of patients with
NBCCS, many of whom present with multiple cysts.
These findings appear logical if we think that in the face, where there is more endogenous fluorescence from porphyrins, excessive fluorescence is more frequent and there are more
nBCCs which have poorer fluorescence.
Of all KCOT cases diagnosed in both services, 40% were associated with
NBCCS. When we evaluated the KCOT cases associated with
NBCCS, and the isolated KCOT cases, we verified that the mean age of the cases associated with the syndrome was 28 years, whereas the mean age for patients without the syndrome was 31 years.
Key words: Odontogenic keratocyst (OKC), Keratocystic odontogenic tumor (KCOT), Nevoid basal cell carcinoma syndrome (
NBCCS).
First described in 1960,
NBCCS is an autosomal dominant condition that can cause unusual facial appearances and a predisposition for basal cell carcinoma, a malignant type of skin cancer.
In large military organizations, the WMD center is called the Nuclear, Biological, and Chemical Center (
NBCC) and is operated by trained WMD technical specialists.
Aggressive modalities have generally been recommended for
NBCCS cases, large KCOTs and recurrent lesions.
The gene is part of the same pathway implicated in nevoid basal cell carcinoma syndrome (
NBCCS) or Gorlin-Goltz syndrome, though its expression is less severe.
(2-4) However, no one has reported an FR of the tongue in a patient with nevoid basal cell carcinoma syndrome (
NBCCS).
(6,7,8) They do not occur in patients with Naevoid Basal Cell Carcinoma Syndrome (
NBCCS).