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According to the current approach (7,15), we accepted 10 ng/mL concentration of 17-OH-P as the cut-off point to define NCAH. After ACTH stimulation 3 of BD patients (10.3%) and 5 AS patients (33.3%) had increased 17-OH-P concentrations >10 ng/mL.
Those 3 patients with BD, 5 patients with AS and one of healthy controls were considered as NCAH or possible heterozygous carriers of CYP21A2 mutations for CAH.
The prevalence of NCAH is relatively high among females with hirsutism or polycyctic ovary syndrome (7,15-20), however there is no data about the frequency of mutation carriers in Turkish healthy population.
There are also different views on the cut-off concentration of stimulated 17-OH-P to define NCAH, mainly due to variations in the main aims of definitions.
Stress doses of GC should not be given to patients with NCAH unless their adrenal function is suboptimal or iatrogenically suppressed.
APHIS, which is USDA's regulatory arm for diagnosing animal diseases and licensing vaccines and diagnostics, will have two centers within the NCAH: the National Veterinary Services Laboratories (NVSL) and the Center for Veterinary Biologics (CVB).
"The new NCAH quarters will facilitate even stronger partnerships between ARS and APHIS," she says.
Scientists will have access to state-of-the-art Biosecurity Level 3 (BSL-3) animal-containment facilities at NCAH to study a range of endemic, zoonotic, and foreign animal diseases.
The NCAH, based in Sandyford, helps tackle inequalities in health, and Mr Forbes said: "We are a small charity and were concerned to get a threatening court summons, particularly as we pay so diligently."
A council spokesman said: "As soon as NCAH contacted us and we realised what had happened we agreed to withdraw the summons and reinstate the instalment arrangements."
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