NCGNNecrotizing and Crescentic Glomerulonephritis
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In a mouse model of antineutrophil cytoplasmic antibody (ANCA) necrotizing and crescentic glomerulonephritis (NCGN) induced by anti-mouse myeloperoxidase (MPO), C5aR1 engagement was harmful, while C5aR2 had the protective and anti-inflammatory effect [88].
Lu, Harvard IC-induced acute lung injury Medical School, USA Anti-mMPO-induced ANCA NCGN CLP-induced sepsis and in vitro assays on leukocytes CLP-induced sepsis Acute pyelonephritis Renal I/R injury Experimental cerebral malaria S.