NESTROFTNaked Eye Single Tube Red Cell Osmotic Fragility Test
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Result of NESTROFT is compared with result of other studies.
Mentzer's index and England & Fraser had more sensitivity and specificity than NESTROFT.
The tests such as MCV, MCH, NESTROFT, Mentzer's index, England & Fraser index have low sensitivity and specificity, as seen in the results, and should not be used for screening BTT as there are greater chances of false positive and false negative.
Alone NESTROFT and other indices should not be used for screening BTT.