NESTROFTNaked Eye Single Tube Red Cell Osmotic Fragility Test
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Table 2 shows 23 (2.3%) true positive cases and 20 (2.0%) false positive cases by NESTROFT. Similarly 18 cases (1.8%) are false negative and 59 cases (5.9%) are true negative by NESTROFT.
Result of NESTROFT is compared with result of other studies.
Mentzer's index and England & Fraser had more sensitivity and specificity than NESTROFT. Cases suspected by these indices are 120 and of which 41 cases are of BTT.
The tests such as MCV, MCH, NESTROFT, Mentzer's index, England & Fraser index have low sensitivity and specificity, as seen in the results, and should not be used for screening BTT as there are greater chances of false positive and false negative.