Neutrophil Gelatinase-Associated Lipocalin (NGAL
) and Kidney Injury Molecule 1 (KIM1) in patients with diabetic nephropathy: A cross-sectional study and the effects of lisinopril.
BioPorto A/S (CPH:BIOPOR), an in-vitro diagnostics company, announced on Saturday that the company has received an Additional Information (AI) request letter from the US Food and Drug Administration (FDA) regarding the application for regulatory clearance of the NGAL
Test for risk assessment of acute kidney injury (AKI) in critical ill patients under the age of 22.
In this study, we aimed to demonstrate the frequency of the development of AKI following LPN in patients with healthy contralateral kidney and determine the early predictive effects of serum NGAL
levels on ischemia--reperfusion injury and its association with WIT.
The ratios of five biomarkers to creatinine were greater in the urine of diabetic patients with normoalbuminuria than in controls ( P < 0.001 in podocalyxin, nephrin, and KIM-1; P < 0.010 in NGAL
; and P < 0.050 in podocin).
Additionally, in accordance with histopathological findings, the biochemical parameters of BUN, creatinine and NGAL
showed no protective effect of LIPC on renal IR injury.
The results demonstrated that NGAL
miR-124 and miR-290-5p decreased by 47% and 78%, respectively, after CLP surgical operation, which were restored by propofol treatment in septic mice.
marks cystic disease in HIV-associated nephropathy.
Enzyme-linked immunosorbent assay using kit from Abcam's Human LCN2 (NGAL
) in vitro ELISA kit assessed plasma level of LCN2.
Urine levels of NGAL
, KIM-1, and IL-18 were measured at baseline and at 2, 4, and 12 hours post-TAVI using the enzyme-linked immunosorbent assay method (Hycult Biotech Inc., Plymouth Meeting, PA).
Vega de Ceniga et al., "Increased plasma levels of NGAL
, a marker of neutrophil activation, in patients with abdominal aortic aneurysm," Atherosclerosis, vol.
We also determined the levels of three recently developed protein markers of kidney injury, namely, KIM-1, cystatin C, and NGAL
using enzyme-linked immunosorbent assay (ELISA) (R&D Systems, Minneapolis, MN).
Previously, we have shown that control neutrophils during 20 min of adhesion to fibronectin secreted lactoferrin (LF), neutrophil gelatinase-associated lipocalin (NGAL
), lysozyme, and myeloperoxidase (MPO), as well as albumin and cytosolic S100A8 and S100A9 proteins [40, 41].