The obvious angling destination for nilos is Kariba, with a few notable locations in particular, though the species are prevalent throughout the lake.
Wherever you choose to fish for nilos the best times are between November and May; any particular month dependent on what extremes of summer heat you're willing to subject yourself to.
The view of some Ichthyologists is that as nilos are an introduced species they must be caught and killed--'hook and cook' as opposed to 'catch and release'.
Personally, I believe nilos are too prolific and will always be around no matter how much you feed them.
This is a topic of much debate and has evolved since the first years when nilos appeared in the lake.