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NINDSNational Institute of Neurological Disorders and Stroke (US National Institutes of Health)
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We need to identify effective, long-term treatment strategies that will help these brave men and women enjoy the highest quality of life possible following their service to our country," said Walter Koroshetz, MD, director of NINDS.
Since our initial NIH BPN award in 2011, AMRI has provided discovery chemistry services to NINDS and its private sector BPN members on 15 drug candidate programs, and two of these programs have advanced to the stage where a pre-clinical candidate has been declared, with a third candidate pending.
Jim Koenig, from the NINDS, said: "These results may have broad implications for multiple neurological disorders.
These trials are the two NINDS trials (parts 1 and 2), the first two ECASS trials, two Alteplase Thrombolysis for Acute Noninterventional Therapy in Ischaemic Stroke (ATLANTIS) trials and Echoplanar Imaging Thrombolytic Evaluation Trial (EPITHET).
Kovach, President and CEO of Lixte, said, "Studies with the research team at the Molecular Pathogenesis Unit, Surgical Neurology Branch, NINDS, identified a biomarker that appears to be preferentially targeted by novel anti-cancer drugs currently being evaluated by NINDS and Lixte as new treatments for human brain tumors.
What will the neuroscience research landscape look like in 15 years, and how can NINDS best contribute?
SRI welcomes the opportunity to provide the NINDS with all the support necessary to develop promising candidates from preclinical assessment through IND," said Carol Green, Ph.
Here, visitors can learn more about what clinical trials really are; those who wish to participate in a clinical trial can choose from an extensive list of neurological conditions, from ADHD to Zellweger syndrome, to see what research is in progress or coming up at the NINDS and elsewhere across the country.
According to the NINDS, about 700,000 Americans suffer a stroke each year.
In February 1998, the NIH Office of Alternative Medicine, along with six NIH institutes, including NIAMS and NINDS, and the Agency for Health Care Policy and Research, issued a PA entitled "Acupuncture Clinical Trial Pilot Grants.
The NINDS is the Federal Government's focal point for research on HD.
AMRI has been collaborating with NINDS since 2005 on novel treatments for spinal muscular atrophy, a degenerative neuromuscular disease.