The NMZL has various different patterns, including nodular, "marginal zonelike," or perifollicular, interfollicular, and diffuse.
By that definition, they found that 20% of their NMZL cases (5 out of 25) were transformed.
In NMZL, along with clinical parameters, treatment decisions are influenced by the morphologic description of an increased number of large cells or a high proliferative index rank.