NNBP

AcronymDefinition
NNBPNon-Nucleoside Binding Pocket
NNBPNamibian National Biodiversity Programme (est. 1944)
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References in periodicals archive ?
The cleavage of caspase-3 was consistently detected in pigs undergoing NNBP and NHCA.
Intact and degraded cTnI were present in pigs undergoing NNBP or NHCA (Figure 6(a)).
More importantly, the percentage of degraded cTnI was significantly lower in NNBP (9.1% [+ or -] 1.5%) than in NHCA (17.2% [+ or -] 2.1%) (Figure 6(b)).
Representative short-axis MR cine images from end-diastole to end-systole during the whole cardiac cycle in pre-CPB, NHCA, and NNBP post-CPB are illustrated in Figure 7(a).
LV end-diastolic volume was significantly lower in NNBP post-CPB (122.5 [+ or -] 2.9) than in NHCA post-CPB (130.6 [+ or -] 4.1 mL) (Figure 7(b)).
The recent study was undertaken to examine the cardio-protective effect of NNBP on myocardial tissue perfusion, cardiac myocyte apoptosis, myocardial stunning, and heart contractile function in hypertrophied hearts.
NNBP maintains normal electromechanical activity and avoids hyperkalemic cardioplegia, thus alleviating coronary endothelial dysfunction, preserving coronary endothelium integrity, and enhancing myocardial blood infusion.
NNBP improves myocardial tissue blood perfusion, provides adequate nutrients and oxygen, washes out all the metabolic waste, and impedes the occurrence of ischemia and reperfusion injury.
The recent study indicated that NNBP enhanced myocardial perfusion, depressed cardiac myocyte apoptosis, decreased myocardial stunning, and improved heart contractile function in comparison with traditional NHCA.
NNBP was superior to NHCA in enhancing myocardial tissue perfusion, inhibiting myocardial cTnI degradation, and alleviating cardiac myocyte apoptosis and preserving heart contractile function in hypertrophied hearts for valve surgery.
Caption: Figure 3: Near infrared myocardial ICG perfusion images and time-ICG absorbance value curves during NNBP and NHCA.
(a) TUNEL-positive nuclei (red) were significantly less in NNBP compared with NHCA.