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First, the corpus contains data from a number of resources, including the product names, names of organizations, descriptions of phenomena, restaurant menus, which we expected to contain a fair number of NNN compounds.
Mark Davies to get NNN strings and to rank them in order.
For the experiment for English and Japanese recursive compounds, eight monolingual native speakers of English and Japanese, aged between 30 and 80, were asked to provide their intuitive interpretation for each target NNN string.
For example, for the NNN string of vanilla ice cream, the participants' interpretation was 'vanilla-flavoured ice cream', so it is a right-branching recursive compound.
Table 1 describes the two study groups (infants with toenail Hg data, n = 41; and infants with NNNS data, n = 151).
We performed supervised clustering of samples with NNNS profiles using 339 Hg-associated loci (see Supplemental Material, Figure S1), but observed no obvious clustering pattern of high-risk neurobehavioral profile.
We then examined the average extent of methylation across all of the EMID2 loci in the NNNS subset, comparing those infants in the high-risk and non-high-risk groups.
Because of previously reported links between Hg and neurodevelopmental deficits and numerous Hg-variable genes involved in neurodevelopment, we examined these loci for associations with a high-risk newborn neurobehavioral profile defined by the NNNS, which are associated with later-life behavioral outcomes (Lester and Tronick 2004; Liu et al.
Compared with other infants in the HOME Study, this infant had high NNNS scores for excitability, lethargy, and stress abstinence (reflecting a higher level of the neurobehavioral dimension) and lower scores for regulation and quality of movement (Table 4).
Abnormal findings in case Neurobehavioral NNNS exam symptoms Displayed hypertonicity in Excessive or trunk, neck, and upper/lower above-normal extremities muscle tone or tension; the infant's musculature becomes "stiff" or rigid, and the infant shows marked resistance to passive movements.
Ten singleton infants in the cohort were referred to a physician for abnormal NNNS findings after the 1-month examination.
The NNNS is a validated tool to assess neurobehavior during early infancy (Lester and Tronick 2004).
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