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Related to NOAEL: LOAEL
NOAELNo-Observed-Adverse-Effect Level (toxicology studies)
References in periodicals archive ?
TTC is an approach based on existing data, notably NOAEL of some kind.
Calabrese's team reviewed hundreds of toxicology papers that document a biological effect below the NOAEL for chemical poisons.
For example, the estimation of the NOAEL is sufficient information for a decisionmaker who seeks to reduce the exposure of the maximally exposed individual to a level equaling the NOAEL divided by some safety factor.
2011) compared BMDLs and NOAELs to the SNCD, using values derived from fitting concentration-response data from the U.
Rather than using this as the PoD, a benchmark dose (BMD) can be used, which is a value that is derived mathematically by fitting a curve to the dose-response data for the critical effect, and is equivalent to a NOAEL.
If the calculated NOAEL for the most highly exposed individual in the Seychelles study (25.
According to an interim report on the project released in November, levels for each of 23 measured elements mostly metals generally fall well below the NOAEL (no observable adverse effects level) set by the Environmental Protection Agency for land application of sewage sludge.
However, the NOAEL depends on the spacing of the data points and hence is not always accurate.
Environmental Protection Agency (EPA) as the NOAEL and LOAEL values for BPA (Hengstler et al.
NOAEL or LOAEL); 4) calculation of the ADE/PDE by application of adjustment factors (also called uncertainty factors, assessment factors, safety factors, etc.
The NOAEL of MECB determined was 2000 mg/kg bodyweight/day (Copplestone 1988).