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NOMIDNeonatal Onset Multisystem Inflammatory Disease
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The filing of Kineret for CAPS and NOMID in the EU and the US respectively are important milestones on Sobi's journey to increase our support for the pediatric rheumatology field as well as for the rare disease community as a whole," said Dr.
IL-1 is overproduced in NOMID and a number of other diseases, leading to damaging inflammation.
Otras mutaciones del NALP3 estan implicadas en el sindrome de Muckle-Wells (MWS, OMIM 191900) y el sindrome CINCA (OMIM 607115, tambien conocido como NOMID o "neonatal-onset multisystem inflammatory disease).
NOMID, also known as chronic infantile neurologic cutaneous articular (CINCA) syndrome, is an inflammatory disorder that affects numerous organs and body systems, including the skin, joints, eyes and central nervous system.