NORVITNorwegian Vitamin Trial
References in periodicals archive ?
Patient diet: NORVIT was conducted in Scandinavian patients who typically consume a diet rich in fish -- which contain heart-healthy omega 3 fatty acids.
Results are shown separately for NORVIT and WENBIT participants (WENBIT, 1 month; NORVIT, 2 months).
We compared results among the NORVIT and WENBIT participants after the exclusion of 321 cases of AMI from WENBIT, thereby essentially comparing patients with recent myocardial infarction (NORVIT) to patients with stable angina pectoris (WENBIT).
Compared to WENBIT (in which most participants had stable CAD), participants in NORVIT (AMI at baseline) had lower circulating concentrations of folate, PLP, and riboflavin, and higher concentrations of tHcy.
We found that for self-reported current smokers in the NORVIT trial log-transformed plasma cotinine decreased linearly as a function of time since hospital admittance.
Timing also makes him skeptical about the NORVIT results.
Mason also wonders whether the 800 mcg of folic acid used in the NORVIT study was too much.
The monitoring board for the VITA-TOPS study explicitly decided not to stop its trial after NORVIT," he notes.
The primary end point in NORVIT was a composite of fatal and nonfatal MI and stroke.
He agreed that the NORVIT cancer findings warrant further study.
NORVIT was sponsored by the Norwegian Research Council, the Norwegian Council on Cardiovascular Research, and other nonprofit institutions, with no industry support.