NSCCMNepalese Society of Critical Care Medicine (Kathmandu, Nepal)
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As demonstrated in Figures 2(a), 2(b), and 2(f), NSCCM significantly reduced the number of apoptotic cells in the ischemic hemisphere, compared to the control group.
NSCCM include neurotrophic factors, like GDNF and BDNF, while BDNF or GDNF was confirmed to exert antiapoptotic effect after transient middle cerebral artery occlusions in rats [28, 29].