Some ILD subtypes, such as the NSIP
and OP, have a better response to corticosteroids than other subtypes.
According to her, some of the components of the NSIP
initiated by President Muhammadu Buhari administration and supported by Gov.
Nonspecific interstitial pneumonia (NSIP
) pattern predominates in most CTD-ILD whereas usual interstitial pneumonia (UIP) pattern is more common in RA.
In this study, 4 (8%) of our patients were diagnosed to have NSIP
on TBLB, they also had a high pre-test probability of NSIP
but were not agreed to undergo surgical lung biopsy which is the recommended procedure for confirmation of diagnosis13.
In this study, we analyzed the expression pattern of TAZ in both cellular and fibrotic NSIP
These findings are compatible with NSIP
. Axial HRCT study (a) and sagittal reconstruction (b).
Although not significant, the same trend was observed in the non-CTD-ILD NSIP
In the present study, we immunohistochemically characterized [CD68.sup.+] and [CD163.sup.+] macrophages in the three subtypes of IIPs: IPF/UIP, NSIP
, and COP.
The American Thoracic Society/European Respiratory Society Statement on Update of the International Multidisciplinary Classification of the Idiopathic Interstitial Pneumonias 2013 was used in the diagnosis and classification of ILD.11 Interstitial lung diseases were classified into different categories including IPF, non-specific interstitial pneumonitis (NSIP
), hypersensitivity pneumonitis (HP), cryptogenic organising pneumonia (COP), sarcoidosis, connective tissue disease-associated interstitial lung disease (CTD-ILD) and other rare interstitial lung diseases depending upon the patient's clinical presentation, laboratory investigations, lung function tests, environmental exposures, radiological findings and pathological diagnosis if available.
The histological patterns of CADM-ILD vary and include desquamative interstitial pneumonitis, usual interstitial pneumonia (UIP), non-specific interstitial pneumonia (NSIP
), and diffuse alveolar damage (DAD) (5).
As a nationally significant infrastructure project (NSIP
) the development would first require planning approval from the Secretary of State for Business, Energy and Industrial Strategy in a formal process taking 12-18 months.
The final diagnosis was usual interstitial pneumonia (UIP) in 21 patients and nonspecific interstitial pneumonia (NSIP
) in six patients.