established HepG2 cells expressing the NTCP
receptor that are susceptible to HBV infection.
They generated mice that express the human NTCP
protein in their liver cells, allowing these cells to be infected by HBV and HDV.
Finally, research and surveillance activities have also been key for the NTCP
. Since 1997, the INCA has been the "WHO Collaborating Center for Tobacco Control", and is a Latin American reference when it comes to producing materials, training human resources and providing technical support for controlling tobacco use (43).
For each organ, NTCP
depends in a very complex way on the dose and the irradiated volume of an organ.
In vitro cell uptake and membrane vesicle efflux assays using [[sup.3]H] LCATD demonstrated that this amphiphilic molecule can hardly penetrate the cell membrane by passive diffusion, whereas it is quickly taken up by cells expressing the OATP1B1, NTCP
transporters, and effluxed by means of BSEP .
They play a secondary role in liver uptake of conjugated BS since the presence of both OATP1Bs only partly compensates for NTCP
Resultados del indice de anidamiento (NTCP
) de la comunidad de endoparasitos por hospedero, en Valparaiso (Val) y Concepcion (Con) y en los anos 2013 y 2014, en tres especies de peces de Chile central.
was reviewed and government of India introduced RNTCP in 1992 with objectives of 85% cure rate and 70% case finding.
Various other forms of hereditary cholestasis (such as Aagenaes syndrome, North American Indian childhood cirrhosis, cirhin deficiency, Dubin-Johnson syndrome, and Alagille syndrome) may result from rare mutations of genes encoding bile acid synthesis enzymes (CYP7A1 , CYP7B1 , HSD3B7 , and AKR1D1 ), the bile acid receptor farnesoid X receptor (FXR), the Notch signaling pathway, sodium taurocholate cotransporting polypeptide (NTCP
), or tight junction proteins along the canalicular membrane of hepatocytes and cholangiocytes [2, 4, 5].
To strengthen implementation of COTPA, the Government of India enacted pilot-based National Tobacco Control Programme (NTCP
) by setting up tobacco control cells at state levels for effective implementation and monitoring of antitobacco laws and initiatives .
Tsukuda et al., "Evaluation and identification of hepatitis B virus entry inhibitors using HepG2 cells overexpressing a membrane transporter NTCP
," Biochemical and Biophysical Research Communications, vol.