We consider a framework for detection and judgment of evidence of well-characterized hazards, using the concepts of sensitivity, specificity, positive predictive value, and negative predictive value
that are well established for medical diagnosis.
As the surgery was not conducted in all the study subjects, the calculation of sensitivity, specificity, positive predictive value, negative predictive value
and diagnostic accuracy for modified Alvarado scoring was assessed on comparing with combined USG and HPE results.
The sensitivity of CRP in diagnosing sepsis was 98.03%, specificity was 91.0%, positive predictive value (PPV) was 97% and negative predictive value
(NPV) was 93.7%.
This corresponds to a sensitivity of 90.14%, specificity of 100%, and positive and negative predictive values
of 100% and 80.55%, respectively.
In our study sensitivity of MASS was 89.39%, specificity 84.06%, positive predictive value 93.57%, negative predictive value
75.32% and diagnostic accuracy was 87.90% (table-III).
"In this study, for example, screening for DSM-5 alcohol use disorder among adolescents ages 12 through 17 years with a threshold of greater than 3 days with alcohol use in the past year resulted in 99% negative predictive value
and 44% positive predictive value.
There was no significant difference for negative predictive value
between normal D-dimer and the Wells score ≤4 combined with normal D-dimer (93.7% vs.
Based on the data, the sensitivity, specificity, positive predictive value, negative predictive value
, and accuracy of the lactate concentration in the vaginal fluid with a threshold of 4.6 mM for diagnosing PROM were 96%, 97.8%, 98%, 96.1%, and 97%, respectively.
In the current retrospective analysis, the sensitivity, specificity, and negative predictive value
of the depression question were similar across subgroups by age, sex, and race.
Major Finding: Hysteroscopy for the diagnosis of endometrial cancer was associated with 94% sensitivity, 98% specificity, a 73% positive predictive value, and a 99.6% negative predictive value
Each diagnostic medical test has intrinsic strengths and weaknesses that can be quantified by calculation of sensitivity, specificity, positive predictive value, and negative predictive value
. (2) Clinical sensitivity (defined as true-positive/true-positive + false-negative) and specificity (true-negative/true-negative + false-positive) of each individual laboratory often is not directly addressed in proficiency testing (PT), as a relatively large number of samples are required.
We were asked by the dermatopathology community to develop a test with high specificity (i.e., a very high negative predictive value
) which would add a significant degree of confidence in determining a normal diagnosis.