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References in periodicals archive ?
His team found that the compound 5'-iodotubercidin suppresses the growth of neuroblastoma cells and identified a potential new therapeutic approach for the disease, a news release said.
Qian, "High mobility group box 1-mediated autophagy promotes neuroblastoma cell chemoresistance," Oncology Reports, vol.
Undifferentiated stem cells and SKNAS, SHSY5Y, and IMR-32 neuroblastoma cell lines were used as controls.
[69] have demonstrated a new type of heterogeneity in neuroblastoma cell lines and primary tumors by identifying three types of cells: sympathetic noradrenergic cells that are characterized by expression of PHOX2B, HAND2, and GATA3 transcription factors; neural crest cell-like (NCC-like) cells that express FOS and JUN family members but do not express PHOX2B and noradrenergic markers; and a mixed type of cells.
Transfection of micro ribonucleic acid 34-a mimics and antisense oligonucleotides into a neuroblastoma cell line significantly affected cellular activity, migration and invasion (p<0.05_.
Methods: To delineate the potential pathogenic activity of serum antibodies on neurons, pooled sera from seven NBD patients and seven healthy controls were divided into purified immunoglobulin G (IgG) and IgG-depleted serum fractions, and each fraction was administered to cultured SH-SY5Y neuroblastoma cells. Cell death was evaluated with a toxicity assay and terminal deoxynucleotidyl transferase dUTP nick end labeling (TUNEL) staining.
Somatostatin receptors (SSTRs) are variably expressed in neuroblastoma cell lines and tumors, as demonstrated by autoradiography, Western blot, immunohistochemistry, and RT-PCR techniques [17-19].
In addition, the HLA-C mismatch between the donor and the recipient induced killer cell immunoglobulin-like receptor- (KIR-) ligand incompatibility in the graft-versus-host direction to generate natural killer (NK) cell alloreactivity against neuroblastoma cells. The conditioning regimen consisted of fludarabine, melphalan, and total body irradiation (TBI), and tacrolimus with shortterm methotrexate was administrated for graft-versus-host disease (GVHD) prophylaxis (Table 1).
The ovarian cancer cell lines SKOV3 (HTB-77) and the human neuroblastoma cell line SH-SY5Y were obtained from American Type Culture Collection (ATCC); healthy fibroblast cell line K21 was a gift from Dr.
Mouse neuroblastoma cell line, Neuro2a (Shanghai Institute of Chinese Academy of Science, China), was cultured in Eagle's minimal essential medium (MEM), supplemented with 10% fetal bovine serum (FBS, Gibco, USA), 2 mM L-glutamine, 1 mM sodium pyruvate, 100 [micro]g/mL streptomycin and 100 U/mL penicillin, at 37[degrees]C in a 5% C[O.sub.2] humidified atmosphere.
Since the neuroblastoma cell lines like SH-SY5Y lack many of the features of mature neurons, differentiation is needed to induce neuron-like properties such as neurite outgrowth and morphological changes [28,29].
Here, we show that miR-16-1 promotes the aberrant [alpha]-synuclein accumulation via targeting heat shock protein 70 in human neuroblastoma cell line SH-SY5Y.