NF

(redirected from Neurofibromin)
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AcronymDefinition
NFNuclear Factor
NFNewfoundland
NFNorfolk Island
NFNiagara Falls (NY/Canada border)
NFNational Forest
NFNoise Figure
NFNursing Facility
NFNon-Fiction
NFNavy Field (video game)
NFNational Front (GB political party)
NFNo Fear (clothing brand)
NFNear Fine (condition of used merchandise)
NFNeurofibromatosis
NFNo Fault (insurance)
NFNational Formulary
NFNot Fair
NFNew Frontier (Star Trek novel series)
NFNanofiltration
NFNormal Form
NFNew Front (Suriname)
NFNutrition Facts
NFNew Face
NFNear-Field
NFNuclear Fuel
NFNear Field
NFNecrotizing Fasciitis
NFNight Fighter (Aircraft)
NFNo Force (Star Wars)
NFNot Funny
NFNeurofibromatosis, Inc.
NFNeurofibromin
NFNoise Factor
NFNanofarad
NFNetFinity (IBM server model)
NFNoise Filter
NFNatural Frequency
NFNorme Française (French Standard)
NFNotch Filter
NFNational Forum
NFNuestra Familia (Our Family, prison gang)
NFNet Force (Tom Clancy novel series)
NFNational Fine (threading)
NFNanofiber
NFNumber of Failures
NFNear-Far (resistance)
NFNon-Factor
NFNOFORN
NFNaegleria Fowleri (amoeba)
NFNo Food
NFNeutral File
NFNeutron Flux
NFNational Fine (screw thread, Society of Automotive Engineers)
NFNo Funds
NFNorthumberland Fusiliers (British Army)
NFNormalizing Factor
NFNormal Functionality
NFNatural Fluorescence
NFNiteFinder (Nerf gun; Hasbro)
NFNose Fairing
NFNew Frontiers Program
NFNo Figure
NFNuclear Furnace
NFNowa Fantastyka (Polish)
NFNight Foreman
NFNordlands Framtid
NFNintendo Forum
NFNested Factorization (mathematics)
NFAir Vanuatu Limited (IATA airline code)
NFNegative Furnished
NFNordfinans
NFNut Free (food)
NFNasty Factor (baseball)
References in periodicals archive ?
Moreover, the protein sequence alignment showed a high degree of conservation of the amino acid sequence around the T2183 residue in the neurofibromin protein across 12 different species by the UCSC Genome Bioinformatics tool [Figure 1]e.
5) in their report on an adult with neurofibromatosis type 1 who developed chronic myeloid leukemia suggest a possible synergistic action between the absence of neurofibromin and the presence of tyrosine kinase activity of BCR/ABL gene.
Neurofibromatosis type 1 (previously known as von Recklinghausen disease) is an autosomal dominant disorder affecting roughly 1 in 3000 persons and is characterized by the mutation of the neurofibromin gene on chromosome 17q11.
Several tumour suppressor genes have been investigated for a role in aetiology of cancer; for example loss--of--function mutation in a tumour suppressor gene NF1, which encodes Neurofibromin (a Ras GTPase-activating protein; RasGAP) has been reported as a cause of inherited cancer known as neurofibromatosis type 1 [16].
NF1 is caused by mutations in a gene called neurofibromin, or Nf1, which makes a protein with the same name.
Loss of neurofibromin is associated with activation of RAS/MAPK and PI3-K/AKT signaling in a neurofibromatosis 1 astrocytoma.
Loss of neurofibromin in astrocytes has been shown to lead to hyperactivation of one of the RAS isoforms, which may lead to the formation of astrocytomas (16).
The neurofibromatosis 1 gene product neurofibromin regulates pituitary adenylate cyclase-activating polypeptide-mediated signaling in astrocytes.
NF1 is an autosomal, dominantly inherited disorder due to mutations in a gene on chromosome 17, which encodes the protein neurofibromin, a tumor suppressor.
My investigation started by categorizing different populations of mitochondria on the basis of their pattern of movements; recording the effects of motor nerve stimulation on mitochondrial movement and synaptic potentiation, combining time-lapse confocal microscopy with electro-physiological methods; and examining the correlation between the modulation of mitochondrial movements and synaptic potentiation, using rotenone and neurofibromin over-expression.
It encodes neurofibromin, a negative regulator of the Ras oncogene, the inactivation of which leads to cell proliferation and tumor development.
Neurofibromin modulation of ras activity is required for normal endocardial-mesenchymal transformation in the developing heart.