Yin, "Molecular cloning and expression of neuroleukin, a neurotrophic factor for spinal and sensory neurons," Science, vol.
Portetelle et al., "The neurotrophic factor neuroleukin is 90% homologous with phosphohexose isomerase," Nature, vol.
Morgan, "Mouse glucose-6-phosphate isomerase and neuroleukin have identical 3' sequences," Nature, vol.
First described by Gurney and others in 1986, neuroleukin is secreted by lymphocyte cells, stimulates antibody production by other blood cells and influences the growth of neurons in embryos.
That success, suggests Gurney, may have been due to reduce competition: "If you control the infection, you reduce the gp 120 and the neuroleukin can start acting again.'
Neuroleukin's exact role in the adult brain remains unclear.