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NDMRNon-Depolarizing Muscle Relaxant (anesthesia)
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In terms of facilitating rapid endotracheal intubation, rocuronium bromide is the first non-depolarizing muscle relaxant considered to be the replacement for succinylcholine, but at a higher dose.
The aim of the present study was to determine the effect of magnesium sulphate pre-treatment on the onset, duration and recovery of non-depolarizing muscle relaxant and to quantify the haemodynamic effects of administration of MgS[O.sub.4] on the arterial blood pressure.
In contrast, gallamine (a non-depolarizing muscle relaxant) or the venom of the puff adder Bitis arietans reduced the force of contraction.
Many studies have been conducted to minimize these side effects related to use of Succinylcholine, such as addition of pretreatment with non-depolarizing muscle relaxant (Abraham V et al 2008).
Rocuronium Bromide a non-depolarizing muscle relaxant (NDMR) as an alternative to Suxamethonium chloride, a depolarizing muscle relaxant (DMR) for the purpose of intubation of trachea with emphasis on onset of time for muscle relaxation, duration of action, hemodynamic changes and complications if any.
The name of the non-depolarizing muscle relaxant used, the total dose of it used and the total time elapsed from the last dose of non-depolarizing muscle relaxant till the reversal were not recorded on the anesthesia chart, but were recorded separately, This was done to ensure that the anesthesiologist in charge of the recovery room remains blinded as to these details.
This is usually achieved by use of non-depolarizing muscle relaxant.
For possible triggers, there might be an unpredictable sensitivity towards non-depolarizing muscle relaxants leading to postoperative prolonged block which may occur after reversal with neostigmine (7).
Background: The antagonistic actions of anticholinesterase drugs on non-depolarizing muscle relaxants are theoretically related to the activity of acetylcholinesterase (AChE) in the neuromuscular junction (NMJ).
The advent of non-depolarizing muscle relaxants of shorter duration led to a decrease in the use of the suxamethonium/THA technique in the 1980s.
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