'So, identifying persons with pre-diabetes could be a tool to be able to accentuate particularly lifestyle-related factors that can reduce the risk for progression and may actually promote reverting back to normal glucose tolerance
as well as reducing their risk for cardiovascular disease.
Clinical, biochemical, and sociodemographic characteristics of women who progressed to postpartum glucose intolerance (IGT and diabetes) were compared with women with normal glucose tolerance
using univariate analysis.
In the present study, we investigated the association between visit-to-visit BP variability and the status of glucose metabolism, alternating from normal glucose tolerance
(NGT) to intermediate hyperglycemia including IFG, IGT, and diabetes in a large-scale population without CVD.
NGT: normal glucose tolerance
; IGT: impaired glucose tolerance; DM: diabetes mellitus.
Landon said, at least a half-dozen published studies have attempted to clarify the additional benefit of their proposed criteria, analyzing the risk of adverse maternal and fetal outcomes in women who are diagnosed using IADPSG criteria and not treated, versus those with a normal glucose tolerance
Methods: In total, 101 patients with hyperthyroidism were divided into hyperthyroidism with normal glucose tolerance
(TNGT), hyperthyroidism with impaired glucose regulation (TIGR), and diabetes (TDM) groups.
The 2016 study, led by Zhilei Shan, involved 1614 newly diagnosed, drug-naive Chinese Han patients with type 2 diabetes (T2D) and 1614 controls with normal glucose tolerance
. The researchers looked for associations between plasma manganese (categorized in tertiles), polymorphisms in the MnSOD gene, and glucose tolerance.
Some studies demonstrated that women with gestational IGT were at higher risk of adverse pregnancy outcomes as compared with women with normal glucose tolerance
(NGT), but others have attributed these findings to differences in the criteria used to diagnose this condition (4,5).
The study consisted of two groups: 27 volunteers with glucose intolerance and 28 volunteers with normal glucose tolerance
. Their diets incorporated 50 grams of carbohydrates daily from one of honey, white cane sugar or HFCS.
The results of fasting blood glucose were categorized into following groups: Group-1(Normal glucose tolerance
: Fasting blood glucose results less than 5.6 mmol/L), Group-2 (Impaired fasting glucose: results between 5.6 to 6.9 mmol/L), Group-3 (Newly diagnosed diabetes mellitus: results greater than 6.9 mmol/L), and Group-4 (Diagnosed type-2 diabetes mellitus)
Normal glucose tolerance
(NGT) was defined as fasting plasma glucose (FPG) of less than 5.5 mmol/l (100 mg/dl) and 2-h postload glucose of less than 7.8 mmol/l (140 mg/dl).
Annual screening in women with normal glucose tolerance
, and 3-6 monthly testing in women identified to have prediabetes, for at least 10 years post-delivery, is prudent in women with risk factors like diagnosis in early pregnancy, obesity, history of insulin use, and high-risk ethnicity.