(redirected from Nucleotide Reverse Transcriptase Inhibitor)
NtRTINucleotide Reverse Transcriptase Inhibitor
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The nucleotide reverse transcriptase inhibitor Viread has been linked to problems such as increased levels of a substance in the body called creatinine (pronounced "kree-at-n-neen").
Viread is a nucleotide reverse transcriptase inhibitor that can fight HIV, as well as hepatitis B.
There are six main types of antiretroviral drugs that currently exist based on the stage in the viral life cycle where they are targeted: (i) nucleoside reverse transcriptase inhibitors (NRTIs) and nucleotide reverse transcriptase inhibitors (NtRTIs), that work by blocking the reverse transcriptase enzyme so that HIV cannot make new virus copies of itself; (ii) non-nucleoside reverse transcriptase inhibitors (NNRTIs), which work by blocking the enzyme reverse transcriptase and prevent reverse transcription, thus stopping HIV replication; (iii) protease inhibitors (PIs), that work by blocking the activity of protease enzymes.
Nucleotide reverse transcriptase inhibitors (NRTIs) have been used for decades to treat infection with retroviruses, such as HIV, by blocking a key enzyme which they need to make more copies of themselves.
* Nucleoside or nucleotide reverse transcriptase inhibitors (NRTIs) and non-nucleoside reverse transcriptase inhibitors (NNRTIs);
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