The neurovascular unit (NVU) is considered a structural and functional unit of the nervous system.
Therefore, we suspect that calpain may influence traumatic NVU damage through upregulating NF-?B-related inflammation.
tMCAO: Transient middle cerebral artery occlusion BBB: Blood-brain barrier OGD/R: Oxygen-glucose deprivation and reoxygenation ROS: Reactive oxygen species ZO: Zonula occludens NOX: Nicotinamide adenine dinucleotide phosphate oxidases MMPs: Matrix metalloproteinases HDACs: Histone deacetylases tPA: Tissue-type plasminogen activator NVU
: Neurovascular unit TJs: Tight junctional proteins Cav1: Caveolin-1 JAM: Junctional adhesion molecules BMECs: Brain microvessel endothelium cel NF-[kappa]B: Nuclear factor kappa-B CNS: Central nervous system I/R: Ischemic reperfusion CBF: Cerebral blood flow TTC: 2,3,5-Triphenyltetrazolium chloride BWC: Brain water content LDH: Lactate dehydrogenase EB: Evans blue DPI: Diphenyleneiodonium Taq: Tasquinimod.
Abbreviations BBB: Blood brain barrier CNS: Central nervous system CSF: Cerebrospinal fluid GLUT: Glucose transporter GABA: Gama amino butyric acid MSG: Monosodium glutamate NVU
: Neurovascular unit DMT: Divalent metal transporter CURL: Uncoupling receptor and ligand RME: Receptor-mediated endocytosis Bk: Bradykinin NO: Nitric oxide donors SGC: Soluble guanylate cyclase MCT: Monocarboxylate transporters DOPA: Dihydroxy-phenylalanine AME: Absorptive-mediated Tf-FMMs: Transferring-conjugated fluorescein loaded magnetic nanoparticles.
In the context of the NVU
, an obviously crucial role is played by the blood-brain barrier (BBB) and of the blood-spinal cord barrier (BSCB), both in general and with respect to the pathophysiology of chronic pain.
* KSubtile puede instalarse a partir del correspondiente paquete rpm preparado para Mandriva, que podemos obtener en <http://rpms.mandrivaclub.com/rpms/Mandriva_Linux_Team__http _www.mandrivaexpert.com_.html> Lo mismo ocurre con NVU
, en este caso desde
Finally, while first-generation NVUs
allowed a thousand flowers to bloom and chased a wide assortment of product ideas, today's NVU
managers strive to create portfolios of related ventures.
The Netherlands, (114) two Dutch nationals had been heading the Nederlandse Volks Unie ("NVU
"), a political party whose basic principle was that the state should be ethnically homogenous.
This intricate relationship between both vascular and neuronal cells is called implied neurovascular unit (NVU