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OATP1Organic Anion Transporting Polypeptide 1
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References in periodicals archive ?
Stieger, "Rifamycin SV and rifampicin exhibit differential inhibition of the hepatic rat organic anion transporting polypeptides, Oatp1 and Oatp2," Hepatology, vol.
Moreover, the levels of bile acid synthetic enzymes (Cyp7a1 and Cyp27a1) and bile acid transporters (Oatp1, Oatp4, Mrp2, and Ntcp) in the liver were reduced when the mice were provided TMAO.
The best characterized family is the OATP1 family with three transporters OATP1A2, OaTp1B1, and OATP1B3 that transport a number of typical OATP substrates including steroid hormone conjugates, thyroid hormones, prostaglandins, bile acids, and various drugs, for example, statins, antibiotics, and a number of anticancer drugs (for a review see [2]).