To examine the sensitivity of the OGCT in detecting gestational diabetes, women who had normal OGCT results were offered the OGTT, and the proportion of gestational diabetes detected with each test were compared.
Both OGCT and OGTT were performed for a sample group who had a normal OGCT result to evaluate the sensitivity of the OGCT result.
From the total sample of 700 women, we were able to analyze 203 (29%) cases that had normal OGCT to examine the sensitivity of OGCT in detecting gestational diabetes.
Additionally, a larger study should be conducted to examine the sensitivity and specificity of the OGCT and OGTT in obese women.
In 2013, the American Congress of Obstetricians and Gynecologists recommended use of the two-step approach using the 50-g OGCT
. Although the American Diabetes Association endorsed the one-step 75-g, 2-hour OGTT, an independent panel supported by the National Institute of Health Consensus Development Program released a draft statement that evidence is insufficient for adopting the one-step approach.
The 50-g, 1-hour OGCT
was most commonly used for all study participants (in 75% prior to 12 weeks' gestation, in 90% between 12 and 23 weeks' gestation and in 99.6% at 24 weeks' gestation and beyond), followed by FPG (in 24% prior to 12 weeks' gestation, in 9% between 12 and 23 weeks' gestation, and in 0.4% at week 24 of gestation and beyond) and the 100-g, 3-hour oral glucose tolerance test (in 0.4% prior to 12 weeks' gestation, in 1.2% between 12 and 23 weeks' gestation, and in 0.1% at week 24 of gestation and beyond).
Borderline GDM was defined as a positive 50 g OGCT (1 hour venous plasma glucose [greater than or equal to] 7.8 mmol/L) followed by a normal oral 75 g OGTT (fasting venous plasma glucose <5.5 mmol/L and a 2 hour glucose <7.8 mmol/L) .
Three (14%) women reported they were worried and/or had a feeling of failure after learning they had a positive OGCT; however, after being told their OGTT results, they were relieved or no longer felt worried.
They found that the risk of later development of type 2 diabetes rose as the OGCT
The investigators found that the risk of later development of type 2 diabetes rose as the values of the OGCT