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Focusing on rapid genomic diagnostics in pancreatic cancer and targeting treatment in breast and prostate cancers, the partnership builds on previous clinical research between OICR and Thermo Fisher and will inform development of three assays that will be utilized to stratify patients in clinical trials in Ontario and other jurisdictions.
John Bartlett, program director, diagnostic development at OICR. 'This project has the potential to springboard advanced next-generation sequencing to routine clinical use in Ontario and across Canada.'
The OICR/Thermo Fisher team will leverage this advantage by supplementing the new assays with unique DNA/RNA stratification biomarkers - specific to pancreatic, prostate and breast cancer - previously qualified by OICR translational researchers.
OICR also hosts coordinating bodies of the ICGC: the ICGC Secretariat, which supports communication and workshops among ICGC members, the Data Coordination Center, which manages data exchanges between members, and the ICGC Data Portal (at http:// www.icgc.org), which provides the scientific community with access to the data and a suite of query tools.
(1) Department of Pathology and Laboratory Medicine, Mount Sinai Hospital; (2) Department of Clinical Biochemistry, University Health Network; and Departments of (3) Laboratory Medicine and Pathobiology, (4) Molecular Genetics, and 5 Medical Biophysics, University of Toronto; (6) Ontario Institute for Cancer Research (OICR), Toronto, Ontario, Canada; (7) Institute for Molecular Medicine (FIMM), University of Helsinki, Helsinki, Finland; (8) Genome Institute of Singapore (Biomedical Sciences Institutes); (9) National University of Singapore; (10) Health Sciences Authority of Singapore, Singapore; (11) Departamento de Bioquimica y Biologia Molecular, Facultad de Medicina, Universidad de Oviedo, Oviedo, Spain.
He is and has participated in clinical trials for Amgen, Janssen, Medivation, Ontario Institute for Cancer Research (OICR), and Prostate Cancer Canada.
Frozen samples were obtained from the Ontario Tumour Bank, a program established by the Ontario Institute for Cancer Research (OICR).
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