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We investigated whether the expression of AQP3 in abundance was parallel with AQP2 at the apical plasma membrane of the IMCD and the OMCD of HFD compared with the ND.
To investigate whether V2R expression in abundance was similar to the AQP2 and AQP3 in the IMCD and OMCD of HFD, respectively.
In high-fat nutritional obesity of rat, immunolight microscopy revealed weak expression of AQP2 at the apical plasma membrane and intracellular vesicles of principal cells of the IMCD and OMCD. AQP3 and V2R expression also observed a decrease in immunolabelling in the IMCD and OMCD.
En la medula renal del grupo HFD, la microscopia electronica de barrido revelo una expresion debil de AQP2 en la membrana plasmatica apical y las vesiculas intracelulares de las celulas principales de IMCD y OMCD. La expresion de AQP3 y V2R tambien observo una disminucion en el inmunomarcador en IMCD y OMCD.
Immunolight microscopy revealed strong AQP2 expression in the IMCD and OMCD of camel compared with the control.
In adult male rat kidneys, AQP2 expression at the apical cell membrane of OMCD and IMCD was mainly found in the dDAVP-infused rat after 6 days, whereas in control rat, expression of AQP2 tended to be localized to the intracellular membrane vesicles (Poulsen et al.).
8 days of dDAVP administration however up-regulated the abundance of AQP4 in OMCD (Poulsen et al.).
In this study, we observed moderate AQP3 expression in the apical cell membrane in the OMCD of camel, whereas strong expression of AQP3 was observed in the IMCD compared with the control.
In conclusion, comparing with AQP2, AQP3 and AQP4 expression in the OMCD and IMCD at cattle (the control), we showed that strong AQP2 expression at the apical cell membrane in both the IMCD and OMCD of camels; strong expression of AQP3 was observed in the IMCD, and strong expression of AQP4 was observed in the OMCD of camel compared with the control.
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