OPFOSOrthogonal-Plane Fluorescence Optical Sectioning
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This feature, together with a rather complex history (Santi, 2011), has unfortunately led to a proliferation of names and acronyms--light sheet fluorescence microscopy (LSFM), selective plane illumination microscopy (SPIM), digital scanned light sheet microscopy (DSLM), orthogonal-plane fluorescence optical sectioning (OPFOS), and more; all refer to essentially the same combination of sheet illumination and perpendicular detection.