OSUCCCOhio State University Comprehensive Cancer Center (Columbus, Ohio)
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Amanda Harper, OSUCCC -- James Tel: (614) 685-5420 Amanda.
Targeting the hedgehog pathway alone or in combination with the PI3K/AKT pathway could be a novel therapeutic option for treating tamoxifen-resistant breast cancer," said principal investigator Sarmila Majumder, research assistant professor in molecular and cellular biochemistry at the OSUCCC - James.
OSUCCC - James is one of only 41 National Cancer Institute-designated Comprehensive Cancer Centers and one of only four centers funded by the NCI to conduct both phase I and phase II clinical trials.
Wolfe Chair in Human Cancer Genetics and a member of the OSUCCC - James Molecular Biology and Cancer Genetics Program.
Leader Amanda Toland, assistant professor of medicine and a specialist in the genetics of cancer susceptibility at the OSUCCC - James and her collaborators analyzed 222 SCC tumors from 135 organ transplant recipients, who as a group are 65 to 250 times more likely to develop SCC than people in the general population.