P4HA1

AcronymDefinition
P4HA1Prolyl 4-Hydroxylase Alpha-1
References in periodicals archive ?
Semenza, "Hypoxia-inducible factor 1 (HIF-1) promotes extracellular matrix remodeling under hypoxic conditions by inducing P4HA1, P4HA2, and PLOD2 expression in fibroblasts," The Journal of Biological Chemistry, vol.
In the present study, we showed that the mRNA expression of P4Ha1 was significantly higher, and the mRNA expression of MMP-2 and MMP-9 that contributed to collagen degradation was markedly lower in the NRLP3 interfering group than in the control group, resulting in the thickness of fibrous cap and the stabilizing of atherosclerotic plaques.
Gene Forward sequence NLRP3 5'-ATGCCAGGAAGACAGCATTG-3' ABCA1 5'-GCGGACCTCCTGTGGTGTT-3' ABCG1 5'-AAGGCCTACTACCTGGCAAAGA-3' P4Ha1 5'-CCCTAAGGCAACTGGATGAA-3' MMP-2 5'-ACCCAGATGTGGCCAACTAC-3' MMP-9 5'-CCTGGAACTCACACGACATCTTC-3' [beta]-actin 5'-TCATCACTATTGGCAACGAGC-3' Gene Reverse sequence NLRP3 5'-TCATCGAAGCCGTCCATGAG-3' ABCA1 5'-CAAGAATCTCCGGGCTTTAGG-3' ABCG1 5'-GCAGTAGGCCACAGGGAACA-3' P4Ha1 5'-CCCATTTGTTGCCAACTAG-3' MMP-2 5'-TCATTTTAAGGCCCGAGCAA-3' MMP-9 5'-TGGAAACTCACACGCCAGAA-3' [beta]-actin 5'-AACAGTCCGCCTAGAAGCAC-3' TABLE 2: Body weight and serum lipid levels in control group and NLRP3i group.