PACNSPrimary Angiitis of the Central Nervous System
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The diagnosis of PACNS is challenging since there are no defined clinical criteria or specific imaging findings.
However, some infectious pathogens such as Varicella Zoster virus, West Nile virus, Mycoplasma gallisepticum, and Human Immunodeficiency virus have been proposed as etiologies for PACNS [10-12].
Neuroimaging is essential in diagnosing PACNS. Magnetic resonance imaging (MRI/MRA) is more sensitive (75-100%) than computed tomography (CT) scans for detection of vascular changes needed for diagnosis [8].
PACNS is a patchy disease since as many as 25% of the biopsies are falsely negative [16].