PDFF - What does PDFF stand for? The Free Dictionary
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In order to quantify pancreas and liver fat content, we used a previously described advanced chemical shift based gradient-echo MRI technique that estimates PDFF
, which is a standardized and objective measure of fat content [16,17, 20, 21, 23, 24].
Based on the PDFf
(x) of the positive NPW and the membership function [[mu].sub.nn[??]w] (x) of the fuzzy set nn[??]w of a positive NPW, direct or numerical integration may be performed to evaluate the fuzzy probability [r.sub.nn[??]w] * [[mu].sub.nn[??]w (x) in Eq.
LPCN 1144, an oral prodrug of bioidentical testosterone, is being developed as a treatment of non-alcoholic steatohepatitis and is currently being studied in a proof-of-concept MRI PDFF
based liver fat imaging clinical study.
NASH resolution was attained on biopsy in 39% of resmetirom patients who had a positive PDFF