Betsholtz, "Abnormal gastrointestinal development in
PDGF-A and PDGFR- [alpha] deficient mice implicates a novel mesenchymal structure with putative instructive properties in villus morphogenesis," Development, vol.
The platelet-derived growth factor (PDGF) family members,
PDGF-A, -B, -C, and -D, are assembled as disulfide-linked homo- or heterodimers, and two receptor tyrosine kinases, PDGFR-[alpha] and -[beta], which can form homo- and heterodimeric receptor complexes, have been identified [16].