PDGF-B

AcronymDefinition
PDGF-BPlatelet-Derived Growth Factor-B
References in periodicals archive ?
The study found that the PDGF-B signaling in the trophoblasts is suppressing production of Erythropoietin (EPO), a cytokine that controls red blood cell differentiation.
When PDGF-B signaling is lost, excessive amounts of EPO are produced in the placenta, which triggers differentiation of red blood cells in the placental vasculature," said Akanksha Chhabra, study first author and a post-doctoral fellow in Mikkola's lab.
Citation: "Trophoblasts Regulate the Placental Hematopoietic Niche through PDGF-B Signaling;" Akanksha Chhabra, Hanna K.