PDGF-R

AcronymDefinition
PDGF-RPlatelet-Derived Growth Factor and its Receptor
References in periodicals archive ?
c-KIT and PDGF-R are receptors of tyrosine kinases expressed in the testis and they are involved in testosterone production.
With imatinib preventing activation of PDGF-R, Fidler said, the endothelial cells died by apoptosis first, with tumor cells following suit one to two weeks later.
Earlier research by Fidler and colleagues showed PDGF-R activation in metastatic prostate tumors adjacent to the bone but not in tumor cells next to muscle.
The present Competitive Intelligence Report about PDGF-R agonists and antagonists provides a competitor evaluation in the field of platelet derived growth factor receptor (PDGF-R) or PDGF targeting molecules for wound healing, bone formation or treatment of cancer as of October 2009.
While agonists of the PDGF receptor (PDGF-R) so far are only proteins or genes to express the protein, antagonists of PDGF-R mainly are small molecules to inhibit the receptor tyrosine kinase (RTK).