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PDGFBPlatelet-Derived Growth Factor, Beta Polypeptide
References in periodicals archive ?
2,8) The gene rearrangements fuse the collagen type I Al (COLlAl) protein gene on chromosome 17 with the platelet-derived growth factor [beta] chain (PDGFB) on chromosome 22; PDGFB is a potent mitogen and has been implicated in transforming processes via autocrine and paracrine pathways.
Endothelium-specific ablation of PDGFB leads to pericyte loss and glomerular, cardiac and placental abnormalities.