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PDGFCPlatelet-Derived Growth Factor C
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References in periodicals archive ?
In support of this view, the present RNA-Seq data indicated that EGR1 (GeneID 1958), EGR2 (GeneID 1959), PDGFC (GeneID 56034), and PDGFD (GeneID 80310) were all downregulated by E2.
4) confirmed that DEFA6, B-cell CLL/lymphoma 11A (BCL11A), interleukin 33 (IL33), BMP7, ATP binding cassette subfamily B member 1 (ABCB1), CCND2, TNFRSF1B, fibronectin 1 (FN1), semaphorin 6A (SEMA6A), and galanin (GAL) were upregulated and that PDGFC, prostaglandin-endoperoxide synthase 2 (PTGS2), Wnt family member 11 (WNT11), transforming growth factor beta 2 (TGFB2), dickkopf WNT signaling pathway inhibitor 1 (DKK1), bone marrow stromal cell antigen 2 (BST2), GATA binding protein 2 (GATA2), gap junction protein beta 6 (GJB6), SMARCA1, and ADAM metallopeptidase with thrombospondin type 1 motif 6 (ADAMTS6) were downregulated in CTC-MCC-41 cells compared with HT-29 cells.
These authors proposed the existence of 3 novel candidate oncogenes--NME2 (nucleoside diphosphate kinase), EID1/CRI1 (regulator of EP300 and RB1), and PDGFC (platelet-derived growth factor)--and 1 candidate tumor suppressor gene, GSN (cytoskeleton regulator), in MPM.