PDGFRL

AcronymDefinition
PDGFRLPlatelet Derived Growth Factor Receptor-Like (Antibodies)
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Gene Fold upregulation Significance (all time points) FRZB 256.9 *** OMD 72.4 *** PDGFRL 55.7 *** LEPR 29.2 *** IGF2 22.6 *** NGFR 19.6 * MSX1 10.4 ** ANGPTL4 8.2 *** MT2A 7.7 *** SFRP1 7.3 *** TGFBR2 5.7 *** TGFBR3 5.7 *** SPP1 5.5 *** ALPL 4.9 *** SORT1 4.4 *** DVL2 3.2 *** PDGFRA 3.2 *** BMPER 2.8 ** S1PR1 2.8 *** FZD1 2.7 *** CSPG4 2.6 *** FZD4 2.5 *** NGFRAP1 2.4 *** FGFR1 2.1 *** SOX9 0.5 ** NES 0.4 ** VEGFA 0.3 *** SFRP4 0.2 ** Only genes with significant >2-fold induction: * p < 0.05, ** p < 0.01, *** p < 0.001, and *** p < 0.0001.
In contrast, 18 cytokines genes (BMPER, CCL19, CCL20, CCL4, CXCL14, IFNB, IL-12A, IL-17B, IL-17D, IL-17F, IL-19, IL-22, IL-26, IL-7, LIF, NLRC3, TGFA, and VEGFA) and 14 receptor genes (CXCR3, IFITM5, IL-13RA1, IL-17RC, IL-1RAPL2, IL-22RA1, IL-22RA2, ILDR1, LILRA5, LTBP2, PDGFD, PDGFRL, TNFRSF14, and TNFRSF6B) were markedly downregulated by 2.05- to 7.48-fold and 2.1- to 10.1-fold, respectively, in chicken line 6.3 with p < 0.01 and fold [greater than or equal to] 2 (Supplementary Table S4, Figures 4 and 5).