PDSCC

AcronymDefinition
PDSCCPoorly Differentiated Squamous Cell Carcinoma (cancer)
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Similar result was found by Gupta K et al14 in their study which reported the mean LI in WD SCC was 55.333 [+ or -] 7.789; in MDSCC was 43.976 [+ or -] 3.152 and in PDSCC was 80 [+ or -] 5.
of cases Frequency of data cases (n = 129) mutations (%) HNC cases 129 97 (75.19%) Genders Male 65 47 (36.43%) Female 64 50 (38.75%) Median age 55 [less than 67 50 (38.75%) or equal to]55 >55 62 47 (36.43%) Habituated to No habits 16 13 (81.25%) Smoking 7 5 (71.42%) Alcohol 2 Nill (0%) Chewing 35 25 (71.42%) Smoking and alcohol 22 18 (81.81%) Smoking and chewing 2 2 (100%) Alcohol and chewing 31 22 (70.96%) Smoking, chewing, 14 12 (85.71%) and alcohol Tissue differentiation WDSCC 86 64 (49.61%) MDSCC 32 25 (19.37%) PDSCC 11 8 (6.20%) Table 3: Demographic data of healthy volunteers with the distribution of Q787Q genotype.
This might be interpreted as most of the mutation in PDSCC is truncating mutations, which may lead to less protein production and absence of its reactivity in nucleus, which in turn indicate an aggressive nature of PDSCC.