PEA3


Also found in: Medical.
AcronymDefinition
PEA3Polyomavirus Enhancer Activator 3
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TGF-[beta] also directly activates other transcription factors implicated in the regulation of MMPs expression; it induces cell signaling that culminates in the transactivation of AP1, PEA3, NF[kappa]B, SP1, and MEF-2 transcription factors to enhance MMP promoters transactivity [45, 49-52].
Transforming growth factor-beta and matrix metalloproteinases: functional interactions in tumor stroma-infiltrating myeloid cells
Through the FASN/HER2 pathway, ICA is unable to upregulate PEA3 and downregulate HER2 [91].
Targeting FASN in breast cancer and the discovery of promising inhibitors from natural products derived from traditional Chinese medicine
On the other hand, E1A-F, ELP, Sp1, C\EBPbeta, BAF1, GCF, HNF-3, and PEA3 motifs are found in some local isolates but were absent in reference sequences.
Molecular detection, phylogenetic analysis, and identification of transcription motifs in feline leukemia virus from naturally infected cats in Malaysia
(1990) found a SNP in the bGH promoter region, '253' SNP near the binding site of polyoma virus enhancer A binding protein 3 (PEA3) transcription factor.
Identification of single nucleotide polymorphisms (SNPs) of the bovine growth hormone (bGH) gene associated with growth and carcass traits in Hanwoo
Through loss- and gain-of-function approaches, they showed that Fgf signaling emanating from the distal region of the epidermis promotes shh expression in the proximal epidermis but that Fgf/Ras signaling prevents shh expression in the distal epidermis through the induction of pea3 expression and maintenance of wnt5b, an inhibitor of blastemal proliferation.
Mature and juvenile tissue models of regeneration in small fish species
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