After many unsuccessful treatments (like 2 weeks of antibiotics and steroids) and countless blood tests and diagnostic tests, we were referred to infectious disease specialist in the best children hospital in our region in NY where he was diagnosed with PFAPA syndrome.
Overall, since the first treatment, my son never got his PFAPA again.
We assessed CRP and PCT values in PFAPA
patients during their febrile episodes and in two control groups consisting of children with various bacterial or viral infections.
Among stereotypical recurrent fevers, irregular episodes likely indicate a monogenic fever syndrome, while more predictable episodes could be cyclic neutropenia or PFAPA
Key words: PFAPA
syndrome, periodic fever syndromes, childhood
sendromu icin spesifik laboratuvar testleri olmadigindan, enfeksiyon gibi atesin diger olasi nedenleri ekarte edildikten sonra klinik olarak tani alir.
The survey, conducted by other investigators, involved 94 children with PFAPA
and also looked at other therapies.
Hastalik tablosu ilk olarak 1987 yilinda Marshall tarafindan FAPA adi ile tanimlanirken 1989 yilinda hastalik PFAPA
adi ile yeniden tanimlanmistir (6).
Eight of 10 children with severe PFAPA
(periodic fever, aphthous stomatitis, pharyngitis, adenitis) syndrome demonstrated a marked decrease in frequency of episodes in response to colchicine at 0.
Children with PFAPA
syndrome demonstrate a rapid onset of "remarkably high fevers and very red tonsils.
McFarland emphasized the potential morbidity and mortality of surgery and suggested that it be reserved for patients who have had PFAPA
for many years and who are especially desperate.
If the patient still meets diagnostic criteria for PFAPA