The differential diagnosis of PGCG includes lesions with very similar clinical and histological characteristics, such as central giant cell granuloma, which are located within the jaw itself and exhibit a more aggressive behaviour.
The PGCG has numerous foci of multinuclear giant cells and hemosiderine particles in a connective tissue stroma.
In conclusion total surgical excision of the lesion under local anaesthesia along with curettage of its base and elimination of irritating factors is the treatment of choice for PGCG.
11,12] PGCGs account for less than 10% of all hyperplastic gingival lesions.
Although previous reports have detected myofibroblasts in PGCG, (19,21,22) no myofibroblasts were observed in the 10 PGCG samples evaluated in this study.
05 POF (n = 10) 10 (100%) 0 0 PG (n = 10) 10 (100%) 0 0 PGCG (n = 10) 10 (100%) 0 0 (1) P-value was obtained using the Kruskal-Wallis test.
A total of 10 FFHs, 10 PGs, 10 POFs and 10 PGCGs, taken from archival formalin-fixed, paraffin-embedded specimens, were evaluated.
1,2,3 PGCG is reactive lesion occurring on the gingiva and alveolar ridge usually as a result of local irritating factors such as tooth extraction, poor dental restora- tions, food impaction, ill fitting dentures, plaque, and calculus.
Clinical appearance of PGCG can present as polyp- loidy or nodular lesion.
PGCG is a soft tissue lesion that very rarely affects the underlying bone, though the later may suffer superficial erosion.