16) The second membrane-associated form of PGES, mPGES-2, is a 41 kDa protein consisting of 378-385 amino acids, which is structurally distinct from mPGES-1.
The third PGES, cPGES, is a GSH-requiring enzyme that is constitutively expressed in a wide variety of cells and is identical to p23, a co-chaperone of heat shock protein 90 (Hsp90).
The experimental data described above using mPGES-1, mPGES-2, and cPGES KO mice indicated that, among these three PGES enzymes, mPGES-1 may be the primary target in the treatment of inflammatory diseases and cancers.
For small lots that don't have the space for horizontal installation, PGES can install them vertically, but it costs more.
PGES began selling the WaterFurnace in February, and has since installed them in 36 homes and at the Marion County Work Release Center near Salem.
Collectively, PGES will be on the lookout to promote other energy efficient technologies.