PHAHPanasonic Home Appliances Hangzhou Co., Ltd. (China)
PHAHPlanar Halogenated Aromatic Hydrocarbon (toxicology)
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Compounded with the particle from the name of God (Ah, as in Ahman), Lish represents a glorious or supreme being elsewhere in GAEL (3, 9, 17, 21), though the distinction from God's identity is not certain, since in one glyph (Phah ah), ah appears to be a comparative or superlative (GAEL, 9, 13, 17).
The usefulness of dermal CYP1A1 expression as a biomarker of PHAH and PAH exposure in cetaceans is further supported by studies showing that CYP1A1 levels or activity in skin and liver correlate with blubber PCB concentrations in cetaceans (Fossi et al.
Over a four-day period the team exposed young female rats to six different doses of a combination of 18 PHAHs comprising 2 dioxins, 4 dibenzofurans, and 12 PCBs.
These results suggest that the doses required for CYP1A1 induction in bladder are low and indicate that beluga are very sensitive in their responses to PHAH contaminants.
In an attempt to a) clarify the role of CYP1A activity in the toxicity of PAHs and b) explore the possible effects of co-occurring PAH-type CYP1A inducers and inhibitors, we cotreated Fundulus heteroclitus (killifish) embryos with three different AHR agonists [the pHAH 3,3',4,4',5-pentachlorobiphenyl (PCB-126) and the PAHs BNF and BaP] and four CYP1A inhibitors that work by various mechanisms (Table 1).
Polyhalogenated aromatic hydrocarbons (PHAHs) comprise a large class of compounds including polychlorinated dibenzodioxins (PCDDs), polychlorinated dibenzofurans (PCDFs), polychlorinated biphenyls (PCBs), polychlorinated naphthalenes, and polybrominated diphenyl ethers.
This study shows that immunologic measurements and respiratory complaints in adolescents were associated with environmental exposure to polyhalogenated aromatic hydrocarbons (PHAHs).
PHAH body burdens were determined in human serum and follicular fluid obtained from infertile women attending one of the collaborating Centers for Reproductive Medicine.
DMBA and TCDD represent PAHs and PHAHs, respectively, that are ubiquitous chemical classes in the environment that frequently occur as mixtures in human and environmental samples.
The term "dioxins" is used for members of the PHAHs that are structurally related (have similar halogen substitution patterns), are persistent and bioaccumulative, and have a common spectrum of biologic responses mediated via binding to a specific high-affinity cellular protein, the aryl hydrocarbon (Ah) receptor (Van den Berg et al.
Members of this group are often called the polyhalogenated aromatic hydrocarbons (PHAHs).