PI3PI3 Kinase
PI3Protease Inhibitor 3 (gene)
PI3Para Influenza 3 (virus)
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References in periodicals archive ?
At the intracellular level, Ang II was found to work on JAK-2/IRS1-IRS2/PI3 kinase, JNK, and ERK via Ang II receptor type 1 (AT1R), to phosphorylate serine residues of key components of insulin signaling pathway, that is, the insulin receptors, IRS1, and the p85 subunit of PI3 kinase, thereby inhibiting PI3 kinase/AKT signaling pathway.
Salvianolic acid A reverses paclitaxel resistance in human breast cancer MCF-7 cells via targeting the expression of transgelin 2 and attenuating PI3 K/Akt pathway.
In microvascular endothelium, CXCL12 activates the PI3 K/AKT/eNOS signaling pathway, which results in phosphorylation of eNOS and a concomitant increase in NO production [30].
Glass, "PI3 kinase regulation of skeletal muscle hypertrophy and atrophy," Current Topics in Microbiology and Immunology, vol.
"We found that the mice with reduced PI3 kinase activity in specific neurons in the brain gained weight because they were unable to produce this thermogenic response," said Elmquist.
Cells were treated for 1 hour with 1 nM NRG-1,100 nM of the PI3 kinase inhibitor wortmannin, or 1 nM NRG-1 and 100 nM wortmannin combined, n = 3.
One of the recent studies shows that GDF-15 is an autocrine/paracrine factor that attenuates the cardiac hypertrophy in experimental models via SMAD and kinases (PI3 K and ERK) signaling pathways.
Western blotting and real-time quantitative polymerase chain reaction (qRT-PCR) indicated that transgelin 2 may mediate paclitaxel resistance by activating the phosphatidylinositol 3-kinase (PI3 K)/Akt signaling pathway to suppress MCF-7/PTX cells apoptosis.
[23] demonstrated that MAPK and PI3 K pathways were involved in induction of B7-H1 expression in response to IFN-[gamma] in dermal fibroblasts.
Washington, Mar 30 (ANI): Blocking the cellular signalling activity of a protein, called PI3 kinase, could prevent memory loss in fruit flies caused by brain plaques similar to those characteristic of Alzheimer's disease in humans, according to a study.