PIG3

AcronymDefinition
PIG3P53-Inducible Gene 3
References in periodicals archive ?
The up-regulated genes include HIAP1, CRAF1, TRAF6, CASP1, CASP2, CASP3, CASP4, HPRT, GADD45, MCL-1, NIP1, BCL2L2, TRAP3, GSTP1, DAXX, PIG11, UBC, PIG3, PCNA, CDC10, JNK1 and RBP2.
The requirement for the p53 proline-rich functional domain for mediation of apoptosis is correlated with specific PIG3 gene transactivation and with transcriptional repression.
p53-dependent expression of PIG3 during proliferation, genotoxic stress, and reversible growth arrest.