PJIAPrincess Juliana International Airport
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Actemra can be given alone or in combination with methotrexate in patients with PJIA. In 2013, FDA approved the intravenous formulation of Actemra for patients two years of age and older with active PJIA.
The approval is based on data from the JIGSAW-117 study, a 52-week, open-label, multicenter, phase 1b pharmacokinetic /pharmacodynamic bridging study designed to determine the appropriate dosing regimen of Actemra SC across a range of body weights in children with PJIA.
Among them, 47 were diagnosed with oJIA (male/female: 11/36, mean age: 9.6 years, and range: 2.5-15.2), 11 with rheumatoid factor(RF-) negative pJIA (male/female: 4/7, mean age: 10.7 years, and range: 2.9-18.3), and 11 with sJIA (male/female: 7/4, mean age: 9.9 years, and range: 5.1-15.4), according to the International League Against Rheumatism criteria [24].
The report provides comprehensive information on the therapeutics under development for Polyarticular Juvenile Idiopathic Arthritis (PJIA), complete with analysis by stage of development, drug target, mechanism of action (MoA), route of administration (RoA) and molecule type.
Subjects and Methods: A total of 50 patients of PJIA coming to Rheumatology Outpatient Department were recruited in the study after informed consent.
He said that 25% of the 1.7 million annual passenger movements at PJIA were already transfers to surrounding islands such as Anguilla, St Barts, Tortola, Saba, Statia, St Kitts and Nevis, and that his company planned to raise that proportion to 30%.
He told the managing director that the primary goals for the ministry include completing the repair work to reopen the Terminal Building of the Princess Juliana International Airport PJIA and the finalisation of plans to construct the US Preclearance Terminal.
Actemra is not approved for subcutaneous use in people with PJIA or SJIA.
On Tuesday this week, the Council of Ministers held an urgent decision-making session that was attended by members of the Supervisory Board of Directors of Princess Juliana International Holding Company NV (PJIA Holding Company).
In addition, data from recently completed abatacept Phase 3 trials in psoriatic arthritis (PsA) and polyarticular juvenile idiopathic arthritis (pJIA) will be presented.
For dealing with polyarticular-course juvenile idiopathic arthritis (pJIA) and psoriasis, subcutaneous injectable methotrexate therapy known as Rasuvo has also received approval.
Roche announced today that the European Medicines Agency has approved RoACTEMRA to treat children with polyarticular juvenile idiopathic arthritis (PJIA), a rare, chronic and debilitating form of childhood arthritis.