PKC1Protein Kinase C Gene
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This signaling cascade is a linear pathway comprised of calcium-dependent protein kinase (PKC1), a MEKK (BCK1), a pair of redundant MEKs (MKK1/2) and a MAP kinase (MPK1/SLT2) (Figure 1) (2).
Research has shown that caspofungin activates the PKC1 pathway leading to Slt2p phosphorylation, and has identified Wsclp cell surface protein as the sensor for the stress induced by caspofungin (46).
Digital Signature generation and verification based upon PKC1 v1.5 and DSA standards and Diffie-Hellman Key Exchanges is also included.