PKIIProtein Kinase Type II (gene)
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Midazolam can inhibit the transcription activity of lipopolysaccharide-induced nuclear factor KB, the activity of TNF-a, the phosphorylation of p38 mitogen kinase, and the formation of peroxides, which can be blocked by peripheral benzodiazepine agonist PKII 195.
Proline-independent ser/thr residues are phosphorylated by non-PDPKs such as calcium/calmodulin-activated PKII, microtubule affinity-regulated kinase 110, PKA, and casein kinase 1.[13] Protein phosphatase 2A (PP2A) accounts for approximately 70% of all tau dephosphorylation activity in the human brain.[14]